Pressure Cooker Pepperoncini Beef Sandwiches (AKA Instant Pot) combine flavorful, juicy meat, with Sir Kensington's Chipotle Mayo, and brine-y Giardiniera for the perfect 5-star sandwich!
This post is sponsored by Sir Kensington's
Meat, in general, isn't my favorite thing to cook. Becoming best friends with a local butcher who happily does all my prep work has been PRICELESS for miss germaphobe over here. So when I'm craving' this Pressure Cooker Pepperoncini Beef Sandwich with Chopped Giardiniera (this can be found near the pickles in any grocery store), I know my butcher has got my back and I won't have to touch or prep ANY animal products . . . I'm a wimp, I have no problem admitting it.
I've preached before that I can't do bland food. This sandwich is the epitome of flavorful and you'll know it with one bite!
The meat could sing with tastiness all on it's now, but then you add a one-two punch of Giardiniera (best stuff ever!) and Sir Kensington's Chipotle Mayo, and it really is just ridiculously awesome.
I was first introduced to Sir Kensington by this Cauliflower Burger by Pinch of Yum (which I know what you're thinking right now, but I would take this veggie burger over any meat burger for the rest of my life!). I've since become Sir Kensington's obsessed and literally have 6 of their products in my fridge right now.
How could one be so passionate about condiments? Well, let me tell you. 6 months ago, I was a mayo hater, but this Avocado Oil Mayo with just a hint of lime is literally spoon lickin' good. Yep, I lick Mayo from spoons now.
The Yellow Mustard has the best tangy kick ever, the Spicy Brown Mustard made me the best Reuben of my entire life, the Sriracha Mayo stole my heart in this Egg Roll Bowl, the Ketchup takes #1 even with my kids and it has less sugar than the typical grocery store brands, and the Special Sauce I would put on my pancakes just to have another reason to eat it!
I've yet to try the Fabanaise which is a vegan mayo, but Rachael Ray says it's good, so I'm dying to try that one too!
To make things even better, all of the ingredients in Sir Kensington's products are good, clean, and wholesome, and contain perfect amounts of spices to make them uniquely more flavorful than any other condiment brand you'll ever use. Can you understand why I'm getting so psyched over condiments now?
This Pepperoncini Beef Sandwich is actually from our cookbook and is definitely one of the recipes that makes the most appearances around here. Aside from Crio Bru, Breakfast Cakes, and Mason Jar Steel Cut Oats that is! The pictures I took here are new though and may include a ridiculous amount of Chipotle Mayo, because that's exactly how it should be eaten!
Now go make you up the tastiest, most flavorful Pepperoncini Beef you've ever had! Enjoy it on a sandwich first, then in the form of a Pepperoncini Beef Eggroll later in the week. My mouth is watering out of control just thinking of it – perhaps that is gross to admit . . .
Enjoy!
MORE SANDWICH RECIPES I LOVE
PrintPressure Cooker Pepperoncini Beef Sandwiches with Chopped Giardiniera
Juicy, tender shredded Pepperoncini Beef topped with pickled veggies and smothered in Chipotle Mayo. Serve it up with a cup of ice water and a big stack of napkins and enjoy!
- Prep Time: 10 minutes
- Cook Time: 90 minutes
- Total Time: 2 hours
- Yield: 6-8 1x
- Category: Entree
- Method: Pressure Cooker
- Cuisine: American
Ingredients
- 3–4 pound chuck or rump roast, visible fat removed and cut into 2 pieces
- 16 oz jar pepperoncini slices
- 14.5 oz can beef broth
- 1 tablespoon dried oregano
- ½ tablespoon dried parsley
- ½ tablespoon garlic powder
- ½ tablespoon onion powder
- 1 teaspoon dried basil
- 1 teaspoon lemon pepper seasoning
- ¼ teaspoon thyme
- ½ teaspoon pepper
- 2 teaspoons Kosher salt
- 16 oz jar Italian Mix Giardiniera, drained and chopped
- chipotle mayonnaise, (preferably Sir Kensington’s Chipotle Mayonnaise)
- provolone cheese slices
- hoagie rolls
Instructions
- Add entire contents of pepperoncini jar, beef broth, oregano, parsley, garlic powder, onion powder, basil, lemon pepper, thyme, pepper, and salt to the pressure cooker pot. Stir ingredients and add roast pieces. Secure the lid and turn pressure release knob to a sealed position. Cook at high pressure for 90 minutes.
- When cooking is complete, use a natural release.
- Place meat on a plate. Use two forks to shred it, then quickly return it to the pot.
- Preheat broiler. Split buns in half and place under broiler to brown, about 1 minute. Top buns with chipotle mayo, meat, chopped giardiniera, and provolone cheese slices; place under the broiler again to melt the cheese. Serve.
Notes
- Tip 1: When cooking meat, allow pressure to release naturally. This may take 20-30 minutes but it helps ensure juicy, tender meat.
- Tip 2: If meat doesn’t shred or isn’t as tender as you’d like, return to high pressure for another 10-15 minutes.
- Tip 3: Buy 2 silicone rings, that way you can use one for foods likes this with strong smells and save the other for sweet or mild smelling foods.
Keywords: sandwich, Italian sub, spicy sub

I will try this recipe, but I have to say I make a very simple version. Beef and a jar of pepperoncini with juice…nothing else! Put in a crock pot till tender. That’s all the flavor you need. Serve plain, over rice or on a roll with your favorite cheese.
★★★
Nice Savory recipe! I made this last night by taking instruction from your article. My children said it was one of the best beef sandwich I’ve ever made for them. Thanks!
★★★★★
Sarah, I’m excited you all liked it. My kids don’t eat a lot of beef, but they also love this one.
Perfect to pull this out of the freezer after a day of Mardi Gra’ing. No prepping – just throw it in the pot and set the time. Thanks for sharing another great meal!
★★★★★
Glinda, doesn’t it just make you so happy!? I’m glad you enjoyed it!
90 minutes in the pressure cooker? it doesnt turn it into a pile of mush? Has anyone really cooked something 90 minutes in a pressure cooker. That just sounds crazy to me.
Joshua, I’ve done it roughly 15 times or so. It’s one of my favorite recipes!
I guess my favorite sandwich is the old time BLT with crispy bacon and home grown tomatoes !
I am so making this!
Favorite sandwich is a brisket sandwich 🙂
My favorite sandwich is a spinach wrap with turkey, black beans, arugula, hot sauce and hummus.
My all-time favorite sandwich is pretty simple: Good bread, butter, and leftover roast chicken (or turkey), lightly salted. If I’m feeling wild, I’ll spread a bit of leftover cranberry sauce on the turkey version. For my spouse, though, I have to use good mayo or mustard in place of the butter. (Yes, condiments are important in our house!)
Anne, I love the salt tip :). I’m absolutely doing that!
You had me at chipotle! lol ALL the Sir Kensington products that you have just described totally have my mouth watering! I am also printing the cauliflower burger recipe right now. I recently made the pepperoncini beef sandwiches and I couldn’t stop eating it, I can’t even imagine if it could be better with a certain mayo.
My favorite sandwiches (before meeting the above recipe) are:
A breakfast sandwich: two slices of Ezekiel bread with spread good peanut butter (just peanuts and salt), add banana slices, a sprinkle of cinnamon, and if feeling extravagant, a small drizzle of maple syrup.
Lunch or dinner: Bread of choice, with bacon, lettuce, and a home grown tomato, avocado, and spread with homemade garlic mayo. Mmmmmm! Is it time for lunch yet???
I’m not really a sandwich eater but there’s one I can’t resist – my Nana’s ham & cheese sandwich from my childhood. She would take a can of flaked ham, grate some cheddar over it and mash the two up with mayo. I do it a bit differently – I use extra old cheddar and reduced salt ham and add a dash of onion powder with just enough olive oil mayo to hold things together. Not exactly gourmet but definitely my favourite and I think of her every time I eat it! <3
I used to get this crusty, warm French bread with turkey, Brie and tomato sandwich when I lived in Milwaukee. My mouth is watering thinking about that deliciousness!
Favorite sandwich is made with homemade white bread, thick slices of tomato, fresh from the garden with delicious freshly made mayo.
Grilled cheese with Swiss, cheddar and bacon
I don’t eat many sandwiches. I do indulge at Thanksgiving – who doesn’t love a leftover turkey sandwich? I make a turkey sandwich with cranberry sauce and homemade mayo between two slices of dressing. Heat it up in a cast iron skillet like you are making a grilled cheese. Dip in warmed gravy like au jus. Yum. I have found a Great Harvest bakery that makes a stuffing bread at Thanksgiving which is a good substitute.
My favorite is a BLT with just the right tomato and good bacon, not burned or raw.
A Vlasic Garden Fresh spear on the side.
My favorite is a fresh from the garden BLT with avocado! I don’t usually use any mayo but I will have to try the avocado oil one!
Your recipe looks great and I need to try it this fall. My all time favorite sandwich is one my son makes – grilled bratwurst with sautéed green bell peppers and onions. A good smear of mustard on the roll and Sauerkraut on the side complete this great meal!
I love a BLT with fresh garden tomatoes on it! But I also love chicken salad sandwiches with moms chicken salad, of course!
This looks so good! I’m definitely going to have to try it. I love a good burger! Hubby makes those on the grill and I make the sides with my pressure cooker – its a win win this way! 🙂
My favorite sandwich when I eat out is a Rueben. It is how I judge a restaurant.
But to eat at home, I think I would have to go with a good old grilled cheese sandwich. I like to change it up a little, sometimes we add salami or pepperoni, sometimes ham and my BF’s favorite is a fried egg, bacon grilled cheese sandwich for breakfast.
Thinly sliced green apple, bacon and cheddar grilled cheese, with mayo and onion. It’s divine. Apple cuts right through the richness. It’s so fresh and glorious! My husband thinks I’m nuts for loving apples on my grilled cheeses.
My favorite sandwich of all times is a chicken salad sandwich topped with bbq potato chips with a side of bread & butter pickles.
I love a Philly Cheesesteak sandwich.
It’s a toss up between Philly Cheesesteak (done at home in pressure cooker) or a good old pannini with fresh tomatoes, mozzarella, and pesto.
Love LOVE love Sir Kenigston!!!! And this sandwich looks yum!!!
I am a big Rueben fan!!!
My comfort food favorite is a Classic BLT..heavy on bacon!! My mother in law makes the best BLT’s…
I love a fresh from the garden BLT❤
Turkey Rubin for sure!
My favorite sandwich is grilled homemade whole grain bread with colby cheese and sliced onion topped with a little butter.
It takes me to my comfy place bringing back memories of my childhood.
I’ve been trying the recipes you post. They are all Amazing! I especially like the steel cut oats.
Thank you for sharing!
My favorite sandwich is a fresh grilled grouper Reuben, on grilled dark rye with Swiss cheese and coleslaw. I made a similar recipe in my Instant Pot for the Italian Beef but will surely make yours next time. It looks so much better and love the addition of the giardiniera and sauce. Yum. Thanks.
I like egg salad with lettuce.
Being from the South, there’s nothing better than a Summertime tomato sandwich with a freshly picked home-grown tomato! The best way to make it is with white bread and a good mayonnaise. If you want to get fancy, then add some bacon too.
I love me an ooey gooey, Monte Cristo! Completely smothered in jam, of course! Any other way is just not a Monte Cristo. Yum!
Fav Sammie… Monte Cristo
Not a huge fan of sandwiches but if I had to choose….I’d go with a BLT club sandwich with everything.
My favorite lunch sandwich is sweet potato noodles (raw), any color bell peppers, red onion, broccoli and/or cauliflower, cheese, and jalapeño cream cheese. This is wrapped in a flour tortilla. I plan to make your recipe soon. Looks and sounds yummy. I like how you introduce new products that you like, such as the Sir Kensington chipotle mayonnaise. I plan to get one.
Liz, raw sweet potato noodles? You’ve got me curious to try this out!
Watercress and bacon! Yes, old fashioned, chopped, crispy bacon and watercress, mixed with a good mayonnaise. Sublime. From this century, it would be a Cuban sandwich.
Lucy, Oh my goodness! That sounds right up my alley. I can’t wait to try that 🙂